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E5531, a synthetic non-toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide
1. The major pathological responses to Gram-negative bacterial sepsis are triggered by endotoxin or lipopolysaccharide. As endotoxin is shed from the bacterial outer membrane, it induces immunological responses that lead to release of a variety of cytokines and other cellular mediators. As part of a...
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Autori principali: | , , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
1999
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1566082/ https://ncbi.nlm.nih.gov/pubmed/10433491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702596 |
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