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Pharmacological modulation of secondary mediator systems–cyclic AMP and cyclic GMP–on inflammatory hyperalgesia
1. The objective of the present paper was to evaluate the relevance of neuronal balance of cyclic AMP and cyclic GMP concentration for functional regulation of nociceptor sensitivity during inflammation. 2. Injection of PGE(2) (10–100 ng paw(−1)) evoked a dose-dependent hyperalgesic effect which was...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1566065/ https://ncbi.nlm.nih.gov/pubmed/10401557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702601 |
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