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Antiarrhythmic effect and its underlying ionic mechanism of 17β-estradiol in cardiac myocytes

1. The effects of oestrogens on action potential and membrane currents were examined in single guinea-pig atrial myocytes. 2. 17β-estradiol (3–10 μM) shortened the action potential duration without significant changes in the resting membrane potential. E-4031 (1 μM) markedly prolonged the action pot...

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Detalhes bibliográficos
Main Authors: Nakajima, Toshiaki, Iwasawa, Kuniaki, Oonuma, Hitoshi, Morita, Toshihiro, Goto, Atsuro, Wang, Yuepeng, Hazama, Hisanori
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566045/
https://ncbi.nlm.nih.gov/pubmed/10385243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702576
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