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Hyperosmolarity reduces the relaxing potency of nitric oxide donors in guinea-pig trachea

1. Non-responders to inhaled nitric oxide treatment have been observed in various patient groups. The bronchodilatory effect of inhaled nitric oxide was attenuated when the airway lumen was rendered hyperosmolar in an in vivo study on rabbits. We used a guinea-pig tracheal perfusion model to investi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hjoberg, Josephine, Högman, Marieann, Hedenstierna, Göran
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566039/
https://ncbi.nlm.nih.gov/pubmed/10385238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702569
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