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Hyperosmolarity reduces the relaxing potency of nitric oxide donors in guinea-pig trachea

1. Non-responders to inhaled nitric oxide treatment have been observed in various patient groups. The bronchodilatory effect of inhaled nitric oxide was attenuated when the airway lumen was rendered hyperosmolar in an in vivo study on rabbits. We used a guinea-pig tracheal perfusion model to investi...

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Hlavní autoři: Hjoberg, Josephine, Högman, Marieann, Hedenstierna, Göran
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566039/
https://ncbi.nlm.nih.gov/pubmed/10385238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702569
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