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Hyperosmolarity reduces the relaxing potency of nitric oxide donors in guinea-pig trachea

1. Non-responders to inhaled nitric oxide treatment have been observed in various patient groups. The bronchodilatory effect of inhaled nitric oxide was attenuated when the airway lumen was rendered hyperosmolar in an in vivo study on rabbits. We used a guinea-pig tracheal perfusion model to investi...

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Detalhes bibliográficos
Main Authors: Hjoberg, Josephine, Högman, Marieann, Hedenstierna, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566039/
https://ncbi.nlm.nih.gov/pubmed/10385238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702569
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