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Endothelium is required in the vascular spasm induced by tetraethylammonium and endothelin-1 in guinea-pig aorta

1. To investigate the role of endothelium in vascular spasm, we studied the influence of endothelin-1 (ET-1) on the contracting and spasmogenic effect of the K(+)-channel blocker, tetraethylammonium (TEA), in aorta rings of reserpine-treated guinea-pigs, perfused with either control (5.5 mM) or elev...

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Detalhes bibliográficos
Main Authors: Dorigo, P, Maragno, I, Santostasi, G, Fraccarollo, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566029/
https://ncbi.nlm.nih.gov/pubmed/10385252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702557
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