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Tonic inhibitory action by nitric oxide on spontaneous mechanical activity in rat proximal colon: involvement of cyclic GMP and apamin-sensitive K(+) channels
1. The cellular mechanisms by which endogenous nitric oxide (NO) modulates spontaneous motility were investigated in rat isolated proximal colon. The mechanical activity was detected as changes in intraluminal pressure. 2. Apamin (1–100 nM) produced a concentration-dependent increase in the amplitud...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1566019/ https://ncbi.nlm.nih.gov/pubmed/10385253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702537 |
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