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Gi-protein α-subunit mRNA antisense oligonucleotide inhibition of Gi-coupled receptor contractile activity in the epididymis of the guinea-pig

1. We have used a reversible permeabilization method to facilitate the entry of Giα1, 2 and 3 G-protein subunit mRNA antisense or mismatch oligonucleotides into intact tissue, to investigate the G-protein α-subunit coupling of α(2)-adrenoceptors, neuropeptide Y (NPY) Y(1), and A(1) adenosine recepto...

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Autors principals: Haynes, John M, Selbie, Lisa A, Hill, Stephen J
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565995/
https://ncbi.nlm.nih.gov/pubmed/10369459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702515
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