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L-365,260 inhibits in vitro acid secretion by interacting with a PKA pathway

1. The aim of this study was to analyse the antisecretory mechanism of L-365,260 in vitro in isolated rabbit gastric glands. 2. We showed that compound L-365,260, described as a non-peptide specific competitive CCK-B receptor antagonist, was able to dose-dependently inhibit [(14)C]-aminopyrine accum...

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Autors principals: Oiry, Catherine, Pannequin, Julie, Cormier, Anne, Galleyrand, Jean-Claude, Martinez, Jean
Format: Artigo
Idioma:Inglês
Publicat: 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565992/
https://ncbi.nlm.nih.gov/pubmed/10369481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702505
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