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Pindolol-insensitive [(3)H]-5-hydroxytryptamine binding in the rat hypothalamus; identity with 5-hydroxytryptamine(7) receptors

1. Pindolol-insensitive [(3)H]-5-hydroxytryptamine ([(3)H]-5-HT) binding to rat hypothalamic membranes was pharmacologically and functionally characterized to resolve whether this procedure selectively labels 5-HT(7) receptors. 2. Consistent with a previous report, 3 μM and not 100 nM pindolol was r...

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Detalhes bibliográficos
Main Authors: Clemett, Delyth A, Kendall, David A, Cockett, Mark I, Marsden, Charles A, Fone, Kevin C F
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565990/
https://ncbi.nlm.nih.gov/pubmed/10369478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702503
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