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Evidence for proteinase-activated receptor-2 (PAR-2)-mediated mitogenesis in coronary artery smooth muscle cells

1. This study investigates, whether in addition to the thrombin receptor (PAR-1), the proteinase-activated receptor-2 (PAR-2) is present in vascular smooth muscle cells (SMC) and mediates mitogenesis. PAR-2 is activated by low concentrations of trypsin and the synthetic peptide SLIGRL. 2. Stimulatio...

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Bibliografische gegevens
Hoofdauteurs: Bretschneider, Ellen, Kaufmann, Roland, Braun, Marina, Wittpoth, Michael, Glusa, Erika, Nowak, Gotz, Schrör, Karsten
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565962/
https://ncbi.nlm.nih.gov/pubmed/10372815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702509
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