A non-pungent triprenyl phenol of fungal origin, scutigeral, stimulates rat dorsal root ganglion neurons via interaction at vanilloid receptors

1. A [(3)H]-resiniferatoxin (RTX) binding assay utilizing rat spinal cord membranes was employed to identify novel vanilloids in a collection of natural products of fungal origin. Of the five active compounds found (scutigeral, acetyl-scutigeral, ovinal, neogrifolin, and methyl-neogrifolin), scutige...

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Detalhes bibliográficos
Main Authors: Szallasi, A, Bíró, T, Szabó, T, Modarres, S, Petersen, M, Klusch, A, Blumberg, P M, Krause, J E, Sterner, O
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565912/
https://ncbi.nlm.nih.gov/pubmed/10217528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702440
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