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Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation

1. Cyclo-oxygenase-2 (COX-2) is expressed at sites of inflammation and is believed to be the major source of inflammation-associated prostaglandin synthesis. Selective inhibition of COX-2 has been suggested to produce anti-inflammatory effects with reduced toxicity in the gastrointestinal tract. We...

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Autori principali: Wallace, John L, Chapman, Kevin, McKnight, Webb
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565891/
https://ncbi.nlm.nih.gov/pubmed/10205009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702420
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