N-substituted analogues of S-nitroso-N-acetyl-D,L-penicillamine: chemical stability and prolonged nitric oxide mediated vasodilatation in isolated rat femoral arteries

1. Previous studies show that linking acetylated glucosamine to S-nitroso-N-acetyl-D,L-penicillamine (SNAP) stabilizes the molecule and causes it to elicit unusually prolonged vasodilator effects in endothelium-denuded, isolated rat femoral arteries. Here we studied the propanoyl (SNPP; 3 carbon sid...

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Detalhes bibliográficos
Main Authors: Megson, I L, Morton, S, Greig, I R, Mazzei, F A, Field, R A, Butler, A R, Caron, G, Gasco, A, Fruttero, R, Webb, D J
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565853/
https://ncbi.nlm.nih.gov/pubmed/10188974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702346
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