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Bronchoconstrictor effect of thrombin and thrombin receptor activating peptide in guinea-pigs in vivo

1. Several thrombin cellular effects are dependent upon stimulation of proteinase activated receptor-1 (PAR-1) localized over the cellular surface. Following activation by thrombin, a new N-terminus peptide is unmasked on PAR-1 receptor, which functions as a tethered ligand for the receptor itself....

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Autores principales: Cicala, Carla, Bucci, Mariarosaria, De Dominicis, Gianfranco, Harriot, Pat, Sorrentino, Ludovico, Cirino, Giuseppe
Formato: Artigo
Lenguaje:Inglês
Publicado: 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565816/
https://ncbi.nlm.nih.gov/pubmed/10077241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702303
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