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Mibefradil (Ro 40-5967) inhibits several Ca(2+) and K(+) currents in human fusion-competent myoblasts

1. The effect of mibefradil (Ro 40-5967), an inhibitor of T-type Ca(2+) current (I(Ca(T))), on myoblast fusion and on several voltage-gated currents expressed by fusion-competent myoblasts was examined. 2. At a concentration of 5 μM, mibefradil decreases myoblast fusion by 57%. At this concentration...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Jian-Hui, Bijlenga, Philippe, Occhiodoro, Teresa, Fischer-Lougheed, Jacqueline, Bader, Charles R, Bernheim, Laurent
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1999
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565812/
https://ncbi.nlm.nih.gov/pubmed/10051142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702321
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