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Transcriptional down-regulation of the rabbit pulmonary artery endothelin B receptor during phenotypic modulation

1. We confirmed that endothelium-independent contraction of the rabbit pulmonary artery (RPA) is mediated through both an endothelin A (ET(A)R) and endothelin B (ET(B2)R) receptor. 2. The response of endothelium-denuded RPA rings to endothelin-1 (ET-1, pD(2)=7.84±0.03) was only partially inhibited b...

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Detalhes bibliográficos
Main Authors: Owe-Young, R, Schyvens, C G, Qasabian, R A, Conigrave, A D, Macdonald, P S, Williamson, D J
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565786/
https://ncbi.nlm.nih.gov/pubmed/10051126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702280
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