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The antinociceptive effect of combined systemic administration of morphine and the glycine/NMDA receptor antagonist, (+)-HA966 in a rat model of peripheral neuropathy

1. We evaluated the ability of the functional antagonist at the glycine site of the N-methyl-D-aspartate (NMDA) receptor complex, (+)-(1-Hydroxy-3-aminopyrrolodine-2-one) ((+)-HA966), to modulate the antinociceptive action of systemic morphine in a rat model of neuropathic pain produced by chronic c...

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Detalhes bibliográficos
Main Authors: Christensen, Dennis, Idänpään-Heikkilä, Juhana J, Guilbaud, Gisèle, Kayser, Valérie
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565751/
https://ncbi.nlm.nih.gov/pubmed/9886755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702240
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