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Modelling of the pharmacodynamic interaction between phenytoin and sodium valproate
1. Treatment of epilepsy with a combination of antiepileptic drugs remains the therapeutic choice when monotherapy fails. In this study, we apply pharmacokinetic-pharmacodynamic modelling to characterize the interaction between phenytoin (PHT) and sodium valproate (VPA). 2. Male Wistar rats received...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565741/ https://ncbi.nlm.nih.gov/pubmed/9884091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702235 |
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