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Persistent nicotinic blockade by chlorisondamine of noradrenergic neurons in rat brain and cultured PC12 cells

1. Chlorisondamine (CHL) blocks behavioural responses to nicotine for several weeks or months in rats. Persistent blockade has also been demonstrated ex vivo, in assays of nicotine-evoked striatal dopamine release. Central administration of [(3)H]-CHL leads to long-term retention of radiolabel in ni...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Reuben, M, Louis, M, Clarke, P B S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565714/
https://ncbi.nlm.nih.gov/pubmed/9863650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702215
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