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LU 73068, a new non-NMDA and glycine/NMDA receptor antagonist: pharmacological characterization and comparison with NBQX and L-701,324 in the kindling model of epilepsy

1. The aim of this study was to assess whether a drug which combines an antagonistic action at both NMDA and non-NMDA receptors offers advantages for treatment of epileptic seizures compared to drugs which antagonize only one of these ionotropic glutamate receptors. 2. The novel glutamate receptor a...

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Autors principals: Potschka, H, Löscher, W, Wlaź, P, Behl, B, Hofmann, H P, Treiber, H-J, Szabo, L
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565685/
https://ncbi.nlm.nih.gov/pubmed/9863655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702172
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