Excitatory motor and electrical effects produced by tachykinins in the human and guinea-pig isolated ureter and guinea-pig renal pelvis

1. In isolated tissue experiments, neurokinin A (NKA) produced concentration-dependent contraction of human and guinea-pig ureter (pD(2)=6.7 and 7.2, respectively); an effect greatly reduced (>80% inhibition) by the tachykinin NK(2) receptor-selective antagonist MEN 11420 (0.1 μM). The tachykinin...

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Sonraí Bibleagrafaíochta
Main Authors: Patacchini, Riccardo, Santicioli, Paolo, Zagorodnyuk, Vladimir, Lazzeri, Massimo, Turini, Damiano, Alberto Maggi, Carlo
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1998
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Papers
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565666/
https://ncbi.nlm.nih.gov/pubmed/9846636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702147
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