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Peripheral and/or central effects of racemic-, S(+)- and R(−)-flurbiprofen on inflammatory nociceptive processes: a c-Fos protein study in the rat spinal cord

1. We have evaluated the effects of intravenous or intraplantar racemic-, S(+)- and R(−)-flurbiprofen on both the carrageenan-evoked peripheral oedema and spinal c-Fos immunoreactivity, an indirect index of neurons involved in spinal nociceptive processes. 2. Three hours after intraplantar injection...

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Autors principals: Buritova, Jaroslava, Besson, Jean-Marie
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565603/
https://ncbi.nlm.nih.gov/pubmed/9776348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702053
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