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The transport of the anti-HIV drug, 2′,3′-didehydro-3′-deoxythymidine (D4T), across the blood-brain and blood-cerebrospinal fluid barriers
1. The brain is a site of infection, viral replication and sanctuary for HIV-1. The treatment of HIV-1 infection therefore requires that an effective agent be delivered to the brain. 2′,3′-Didehydro-3′-deoxythymidine (D4T) is a nucleoside analogue which has been shown to have beneficial clinical eff...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565597/ https://ncbi.nlm.nih.gov/pubmed/9776343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702044 |
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