Cytokine induction of NO synthase II in human DLD-1 cells: roles of the JAK-STAT, AP-1 and NF-κB-signaling pathways

1. In human epithelial-like DLD-1 cells, nitric oxide synthase (NOS) II expression was induced by interferon-γ (100 u ml(−1)) alone and, to a larger extent, by a cytokine mixture (CM) consisting of interferon-γ, interleukin-1β (50 u ml(−1)) and tumor necrosis factor-α (10 ng ml(−1)). 2. CM-induced N...

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Detalhes bibliográficos
Main Authors: Kleinert, Hartmut, Wallerath, Thomas, Fritz, Gerhard, Ihrig-Biedert, Irmgard, Rodriguez-Pascual, Fernando, Geller, David A, Forstermann, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565595/
https://ncbi.nlm.nih.gov/pubmed/9776360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702039
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