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Influence of chronic hypoxia on the contributions of non-inactivating and delayed rectifier K currents to the resting potential and tone of rat pulmonary artery smooth muscle

Exposing rats to chronic hypoxia increased the 4-aminopyridine (4-AP) sensitivity of pulmonary arteries. 1 mM 4-AP caused smooth muscle cell depolarization and contraction in arteries from hypoxic rats, but had little effect in age-matched controls. Chronic hypoxia downregulated delayed rectifier K(...

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Detalhes bibliográficos
Main Authors: Osipenko, O N, Alexander, D, MacLean, M R, Gurney, A M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565551/
https://ncbi.nlm.nih.gov/pubmed/9723941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702006
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