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2′,3′-O-(2,4,6- trinitrophenyl) adenosine 5′-triphosphate (TNP-ATP)–a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels

1. P2X receptor activation by α,β-meATP evoked inward currents in acutely dissociated rat mesenteric artery smooth muscle cells and contractions of whole artery rings. 2. The selective P2X(1) and P2X(3) receptor antagonist TNP-ATP inhibited P2X receptor mediated inward currents in response to 3 μM α...

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Hlavní autoři: Lewis, C J, Surprenant, A, Evans, R J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565549/
https://ncbi.nlm.nih.gov/pubmed/9723959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702001
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