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α(2)-Adrenoceptor-mediated contractions of the porcine isolated ear artery: evidence for a cyclic AMP-dependent and a cyclic AMP-independent mechanism

1. The aim of this study was to determine the conditions under which the α(2)-adrenoceptor agonist UK14304 produces vasoconstriction in the porcine isolated ear artery. 2. UK14304 (0.3 μM) produced a small contraction of porcine isolated ear arteries which was 7.8±3.3% of the response to 60 mM KC1....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Roberts, R E, Tomlinson, A E, Kendall, D A, Wilson, V G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565491/
https://ncbi.nlm.nih.gov/pubmed/9720780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701935
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