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Mechanism of neuromuscular blockade induced by phenthonium, a quaternary derivative of (−)–hyoscyamine, in skeletal muscles

1. The mechanisms underlying the postjunctional blockade induced by phenthonium [N-(4-phenyl) phenacyl 1-hyoscyamine] were investigated in mammalian and amphibian muscles. This muscarinic antagonist was previously shown to enhance specifically the spontaneous acetylcholine (ACh) release at concentra...

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Detalhes bibliográficos
Main Authors: Souccar, Caden, Lima-Landman, Maria Teresa R, Ballejo, Gustavo, Lapa, Antonio José
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565488/
https://ncbi.nlm.nih.gov/pubmed/9720800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701932
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