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Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium

1. House dust mite (HDM) allergens with cysteine and serine proteinase activity are risk factors for allergic sensitization and asthma. A simple method to fractionate proteinase activity from HDM faecal pellets into cysteine and serine class activity is described. 2. Both proteinase fractions increa...

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Detalhes bibliográficos
Main Authors: Winton, Helen L, Wan, Hong, Cannell, Mark B, Thompson, Philip J, Garrod, David R, Stewart, Geoffrey A, Robinson, Clive
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565479/
https://ncbi.nlm.nih.gov/pubmed/9720772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701905
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