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SUR2 subtype (A and B)-dependent differential activation of the cloned ATP-sensitive K(+) channels by pinacidil and nicorandil

1. The classical ATP sensitive K(+) (K(ATP)) channels are composed of a sulphonylurea receptor (SUR) and an inward rectifying K(+) channel subunit (BIR/Kir6.2). They are the targets of vasorelaxant agents called K(+) channel openers, such as pinacidil and nicorandil. 2. In order to examine the tissu...

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Autores principales: Shindo, Takashi, Yamada, Mitsuhiko, Isomoto, Shojiro, Horio, Yoshiyuki, Kurachi, Yoshihisa
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565476/
https://ncbi.nlm.nih.gov/pubmed/9692785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701927
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