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Voltage- and use-dependent inhibition of Na(+) channels in rat sensory neurones by 4030W92, a new antihyperalgesic agent

1. Whole cell patch clamp techniques were used to study the effects of 4030W92 (2,4-diamino-5-(2,3-dichlorophenyl)-6-fluoromethylpyrimidine), a new antihyperalgesic agent, on rat dorsal root ganglion (DRG) neurones. 2. In small diameter, presumably nociceptive DRG neurones under voltage-clamp, 4030W...

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Detalhes bibliográficos
Main Authors: Trezise, D J, John, V H, Xie, X M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565468/
https://ncbi.nlm.nih.gov/pubmed/9692781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701919
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