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AT(2) antagonist-sensitive potentiation of angiotensin II-induced constriction by NO blockade and its dependence on endothelium and P450 eicosanoids in rat renal vasculature

1. We showed earlier that NO inhibition caused a left-shift and augmented E(max) of the concentration-response curve of AT(1)-mediated (angiotensin II)-induced vasoconstrictions (AII-VC) in the rat kidney. The 0.01–0.1 nM AII-VC unmasked by the potentiating effect of NO inhibition, were sensitive no...

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Hlavní autoři: Muller, Catherine, Endlich, Karlhans, Helwig, Jean-Jacques
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565462/
https://ncbi.nlm.nih.gov/pubmed/9692780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701906
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