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Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB(1) and CB(2) receptors
The cannabinoid receptor antagonist SR141716A has been suggested to be an inverse agonist at CB(1) receptors in some isolated intact tissues. We found that the basal incorporation of [(35)S]-GTPγS in Chinese hamster ovary cells expressing human recombinant CB(1) and CB(2) receptors was inhibited by...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565455/ https://ncbi.nlm.nih.gov/pubmed/9690851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701915 |
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