T-type and L-type calcium channel blockers exert opposite effects on renin secretion and renin gene expression in conscious rats

1. This study aimed to investigate and to compare the effects of pharmacological T-type calcium channel and of L-type calcium channel blockade on the renin system. To this end, male healthy Sprague-Dawley rats were treated with the T-channel blocker mibefradil or with the L-channel blocker amlodipin...

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Bibliographic Details
Main Authors: Wagner, Charlotte, Krämer, Bernhard K, Hinder, Markus, Kieninger, Martin, Kurtz, Armin
Format: Artigo
Language:Inglês
Published: 1998
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565416/
https://ncbi.nlm.nih.gov/pubmed/9647484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701861
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