Effects of pravastatin on cholesterol metabolism of cholesterol-fed heterozygous WHHL rabbits

1. We administered the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor pravastatin at a daily dose of 1 mg kg(−1) body weight to cholesterol-fed (0.03%) heterozygous Watanabe heritable hyperlipidaemic rabbits, an animal model for heterozygous familial hypercholesterolaemia. 2. After 12 mon...

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Detalhes bibliográficos
Main Authors: Harsch, Michael, Gebhardt, Angelika, Reymann, Andreas, Lang, Gerhard, Schliack, Michael, Löser, Roland, Hinrich Braesen, Jan, Niendorf, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565386/
https://ncbi.nlm.nih.gov/pubmed/9641543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701831
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