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Dual effects of dichloroacetate on cardiac ischaemic preconditioning in the rat isolated perfused heart

1. Ischaemic cardiac preconditioning represents an important cardioprotective mechanism which limits myocardial ischaemic damage. The aim of this investigation was to assess the impact of dichloroacetate (DCA), a pyruvate dehydrogenase complex activator, on preconditioning. 2. Rat isolated hearts we...

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Détails bibliographiques
Auteurs principaux: Randall, Michael D, Keon, Claudia A, Greenhaff, Paul L, Constantin-Teodosiu, Dumitru
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565377/
https://ncbi.nlm.nih.gov/pubmed/9630366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701828
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