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Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT(1A) autoreceptor in vivo

1. It has been hypothesized that 5-HT(1A) autoreceptor antagonists may enhance the therapeutic efficacy of SSRIs and other antidepressants. Although early clinical trials with the β-adrenoceptor/5-HT(1) ligand, pindolol, were promising, the results of recent more extensive trials have been contradic...

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Autors principals: Clifford, Elizabeth M, Gartside, Sarah E, Umbers, Valerie, Cowen, Philip J, Hajós, Mihály, Sharp, Trevor
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565357/
https://ncbi.nlm.nih.gov/pubmed/9630361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701796
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