Endothelium-dependent relaxation and hyperpolarization in guinea-pig coronary artery: role of epoxyeicosatrienoic acid

1. Acetylcholine (ACh) elicits an endothelium-dependent relaxation and hyperpolarization in the absence of nitric oxide (NO) and prostaglandin synthesis in the guinea-pig coronary artery (GPCA). This response has been attributed to a factor termed endothelial-derived hyperpolarizing factor (EDHF). R...

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Bibliographic Details
Main Authors: Eckman, D M, Hopkins, N, McBride, C, Keef, K D
Format: Artigo
Language:Inglês
Published: 1998
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565348/
https://ncbi.nlm.nih.gov/pubmed/9630358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701778
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