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Effect of some cyclooxygenase inhibitors on the increase in guanosine 3′:5′-cyclic monophosphate induced by NO-donors in human whole platelets

1. The effect of the NSAIDs indomethacin, indoprofen, diclofenac and acetylsalicylic acid on the increase in guanosine 3′:5′-cyclic monophosphate (cyclic GMP) induced by nitric oxide-donor agents was tested in human whole platelets and in platelet crude homogenate. 2. In whole platelets, indomethaci...

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Detalhes bibliográficos
Main Authors: Failli, Paola, Cecchi, Enrica, Tosti-Guerra, Cristina, Mugelli, Alessandro, Laffi, Giacomo, Zilletti, Lucilla, Giotti, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565300/
https://ncbi.nlm.nih.gov/pubmed/9579743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701745
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