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Antidepressant-like effects of endogenous histamine and of two histamine H(1) receptor agonists in the mouse forced swim test

1. Effects of substances which are able to alter brain histamine levels and two histamine H(1) receptor agonists were investigated in mice by means of an animal model of depression, the forced swim test. 2. Imipramine (10 and 30 mg kg(−1), i.p.) and amitriptyline (5 and 15 mg kg(−1), i.p.) were used...

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Autors principals: Lamberti, Claudia, Ipponi, Alessandro, Bartolini, Alessandro, Schunack, Walter, Malmberg-Aiello, Petra
Format: Artigo
Idioma:Inglês
Publicat: 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565296/
https://ncbi.nlm.nih.gov/pubmed/9579727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701740
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