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Functional and biochemical evidence for diazepam as a cyclic nucleotide phosphodiesterase type 4 inhibitor

1. The responses of the electrically-driven right ventricle strip of the guinea-pig heart to diazepam were recorded in the absence and in the presence of different selective cyclic nucleotide phosphodiesterase (PDE) inhibitors. 2. Diazepam, at concentrations ranging from 1 μM to 100 μM, was devoid o...

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Detalhes bibliográficos
Main Authors: Carmen Collado, M, Beleta, Jorge, Martinez, Ester, Miralpeix, Montse, Domènech, Teresa, Maria Palacios, José, Hernández, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565256/
https://ncbi.nlm.nih.gov/pubmed/9559885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701698
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