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Phosphodiesterase profile of human B lymphocytes from normal and atopic donors and the effects of PDE inhibition on B cell proliferation

1. CD19(+) B lymphocytes were purified from the peripheral blood of normal and atopic subjects to analyse and compare the phosphodiesterase (PDE) activity profile, PDE mRNA expression and the importance of PDE activity for the regulation of B cell function. 2. The majority of cyclic AMP hydrolyzing...

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Detalhes bibliográficos
Main Authors: Gantner, Florian, Götz, Christine, Gekeler, Volker, Schudt, Christian, Wendel, Albrecht, Hatzelmann, Armin
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565253/
https://ncbi.nlm.nih.gov/pubmed/9559883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701688
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