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Phosphodiesterase profile of human B lymphocytes from normal and atopic donors and the effects of PDE inhibition on B cell proliferation

1. CD19(+) B lymphocytes were purified from the peripheral blood of normal and atopic subjects to analyse and compare the phosphodiesterase (PDE) activity profile, PDE mRNA expression and the importance of PDE activity for the regulation of B cell function. 2. The majority of cyclic AMP hydrolyzing...

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Détails bibliographiques
Auteurs principaux: Gantner, Florian, Götz, Christine, Gekeler, Volker, Schudt, Christian, Wendel, Albrecht, Hatzelmann, Armin
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565253/
https://ncbi.nlm.nih.gov/pubmed/9559883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701688
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