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Emodin-induced muscle contraction of mouse diaphragm and the involvement of Ca(2+) influx and Ca(2+) release from sarcoplasmic reticulum
1. The effects on skeletal muscle of emodin, an anthraquinone, were studied in the mouse isolated diaphragm and sarcoplasmic reticulum (SR) membrane vesicles. 2. Emodin dose-dependently caused muscle contracture, simultaneously depressing twitch amplitude. Neither tubocurarine nor tetrodotoxin block...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565233/ https://ncbi.nlm.nih.gov/pubmed/9535008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701677 |
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