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The inhibitory effect of propranolol on ATP-sensitive potassium channels in neonatal rat heart

1. Whole cell and single channel recordings of ATP-sensitive K(+) current (I(K,ATP)) were carried out in ventricular myocytes isolated from neonatal rat hearts. 2. (±)-Propranolol, a commonly used β-blocker, inhibited the whole cell I(K,ATP) in a concentration-dependent manner with a half-maximal co...

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Détails bibliographiques
Auteurs principaux: Xie, Lai-Hua, Takano, Makoto, Noma, Akinori
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565199/
https://ncbi.nlm.nih.gov/pubmed/9517376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701630
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