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Ethanol-induced inhibition of a neuronal P2X purinoceptor by an allosteric mechanism

Ethanol inhibits a neuronal P2X purinoceptor by shifting the ATP concentration–response curve to the right in an apparently competitive manner. However, the underlying mechanism has not been determined. We investigated the effects of ethanol on the activation and deactivation time constants for ATP-...

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Bibliografiske detaljer
Main Authors: Li, Chaoying, Peoples, Robert W, Weight, Forrest F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565146/
https://ncbi.nlm.nih.gov/pubmed/9484847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701599
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