MEN 11420 (Nepadutant), a novel glycosylated bicyclic peptide tachykinin NK(2) receptor antagonist

1. The pharmacological profile was studied of MEN 11420, or cyclo{[Asn(β-D-GlcNAc)-Asp-Trp-Phe-Dap-Leu]cyclo(2β-5β)}, a glycosylated derivative of the potent, selective, conformationally-constrained tachykinin NK(2) receptor antagonist MEN 10627 (cyclo(Met-Asp-Trp-Phe-Dap-Leu)cyclo(2β-5β)). 2. MEN 1...

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Bibliografiset tiedot
Päätekijät: Catalioto, R-M, Criscuoli, M, Cucchi, P, Giachetti, A, Giannotti, D, Giuliani, S, Lecci, A, Lippi, A, Patacchini, R, Quartara, L, Renzetti, A R, Tramontana, M, Arcamone, F, Maggi, C A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 1998
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Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565144/
https://ncbi.nlm.nih.gov/pubmed/9484857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701587
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