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The effects of a novel sulphidopeptide leukotriene antagonist, BAY x7195, against elicited bronchoconstriction in the anaesthetized guinea-pig

1. The novel leukotriene antagonist Bay  x7195, has been evaluated against bronchoconstriction induced by leukotriene D(4) (LTD(4)), the thromboxane A(2) (TXA(2)) mimetic U46619, histamine and antigen, in the guinea-pig in vivo by use of a modified Konzett-Rössler preparation. 2. LTD(4), given intra...

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Detalhes bibliográficos
Main Authors: Francis, H P, Patel, U P, Thompson, A M, Carpenter, T G, Gardiner, P J, Abram, T S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565138/
https://ncbi.nlm.nih.gov/pubmed/9484852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701580
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