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Distinct inhibitory effects of spinal endomorphin-1 and endomorphin-2 on evoked dorsal horn neuronal responses in the rat
Intrathecal endomorphin-1 and endomorphin-2 (0.25–50 μg) dose-relatedly reduced all components of electrical evoked C-fibre responses of spinal neurones. These effects were partially reversed by naloxone. Endomorphin-1, but not endomorphin-2, dose-relatedly reduced the Aβ-fibre evoked responses. Pea...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1997
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565126/ https://ncbi.nlm.nih.gov/pubmed/9422796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701594 |
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