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Distinct inhibitory effects of spinal endomorphin-1 and endomorphin-2 on evoked dorsal horn neuronal responses in the rat

Intrathecal endomorphin-1 and endomorphin-2 (0.25–50 μg) dose-relatedly reduced all components of electrical evoked C-fibre responses of spinal neurones. These effects were partially reversed by naloxone. Endomorphin-1, but not endomorphin-2, dose-relatedly reduced the Aβ-fibre evoked responses. Pea...

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Detalhes bibliográficos
Main Authors: Chapman, Victoria, Diaz, Alvaro, Dickenson, Anthony H
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565126/
https://ncbi.nlm.nih.gov/pubmed/9422796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701594
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