Assessment of the role of α(2)-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice

1. The role of α(2)-adrenoceptor (AR) subtypes in the modulation of acute nociception, motor behaviour and body temperature, has been investigated by determining the activity of the α(2)AR selective agonist dexmedetomidine (Dex) in mice devoid of individual α(2)AR subtypes through either a point (α(...

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Detalhes bibliográficos
Main Authors: Hunter, J C, Fontana, D J, Hedley, L R, Jasper, J R, Lewis, R, Link, R E, Secchi, R, Sutton, J, Eglen, R M
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565079/
https://ncbi.nlm.nih.gov/pubmed/9421280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701520
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