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Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells in vitro and angiogenesis in vivo

1. First developed as an antiallergic drug, tranilast inhibits chemical mediator release from mast cells. In the present study, we examine the effects of tranilast on angiogenesis in vitro and in vivo and discuss the application of tranilast for angiogenic diseases. 2. Tranilast inhibited significan...

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Detalhes bibliográficos
Main Authors: Isaji, Masayuki, Miyata, Hiroshi, Ajisawa, Yoshiyuki, Takehana, Yasuo, Yoshimura, Nagahisa
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565049/
https://ncbi.nlm.nih.gov/pubmed/9401770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701493
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